Table 8

Subsystem classification for essential reactions predicted for all six E. coli strains under aerobic conditions (n = 282).

Subsystem

Number of essential genes

Percentage(%)


Alternate Carbon Metabolism

3

1.1


Amino Acid Metabolism

151

53.5


Cell Envelope Biosynthesis

41

14.5


Citric Acid Cycle

4

1.4


Cofactor and Prosthetic Group Biosynthesis

72

25.5


Folate Metabolism

3

1.1


Glycerophospholipid Metabolism

12

4.3


Inorganic Ion Transport and Metabolism

7

2.5


Lipopolysaccharide Biosynthesis/Recycling

11

3.9


Membrane Lipid Metabolism

2

0.7


Murein Biosynthesis

2

0.7


Nucleotide Salvage Pathway

8

2.8


Purine and Pyrimidine Biosynthesis

19

6.7


Transport, Inner Membrane

3

1.1


Transport, Outer Membrane

13

4.7


Unassigned

1

0.4


Baumler et al. BMC Systems Biology 2011 5:182   doi:10.1186/1752-0509-5-182

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