Schematic overview of the modular "building block" framework used to construct the Cellular Stress Network. A detailed network model of NRF2 signaling was included in the Oxidative Stress building block. A few examples of relevant transcription factors and kinase cascades included in the network model are shown.
Schlage et al. BMC Systems Biology 2011 5:168 doi:10.1186/1752-0509-5-168