Table 6 |
||||||||
|
Statistics of the pathway database comparison of core metabolic processes |
||||||||
|
Number of (percentage of union) |
||||||||
|
|
||||||||
|
Genes |
EC numbers |
Metabolites |
Reactions |
|||||
|
|
||||||||
|
union |
1723 |
-55% |
959 |
-32% |
2805 |
-40% |
3713 |
-47% |
|
consensus |
264 (15%) |
+ 2% |
180 (19%) |
+ 1% |
316 (11%) |
+ 2% |
144 (4%) |
+ 1% |
|
majority score |
875 (51%) |
+ 9% |
508 (53%) |
+ 3% |
757 (27%) |
+ 6% |
674 (18%) |
+ 4% |
|
|
||||||||
|
Database |
Unique per database (percentage of union) |
|||||||
|
|
||||||||
|
BiGG |
75 (4%) |
+ 3% |
63 (7%) |
+ 4% |
276 (10%) |
- 1% |
621 (17%) |
- 1% |
|
EHMN |
186 (11%) |
+ 8% |
125 (13%) |
+ 7% |
910 (32%) |
+ 7% |
1129 (30%) |
+ 4% |
|
HumanCyc |
70 (4%) |
-16% |
62 (6%) |
-15% |
243 (9%) |
- 7% |
326 (9%) |
- 4% |
|
KEGG |
180 (10%) |
+ 8% |
45 (5%) |
+ 4% |
209 (7%) |
+ 1% |
274 (7%) |
+ 2% |
|
Reactome |
19 (1%) |
- 3% |
8 (1%) |
0 |
80 (3%) |
- 6% |
154 (4%) |
- 4% |
|
|
||||||||
|
Total |
530 (31%) |
+ 1% |
303 (32%) |
0 |
1718 (61%) |
- 6% |
2504 (67%) |
- 3% |
|
|
||||||||
|
Genes: Entrez Gene IDs, including genes encoding for a component of a protein complex as separate entities. EC numbers: only fully specified EC numbers. Metabolites: if two metabolites of one database both match the same metabolite in another database this is counted as one match. Reactions: reactions where not required to match on e-, H+ and/or H2O. Differences with the outcomes of the global comparison (Table 3) are indicated in percentages for each level of comparison. |
||||||||
|
Stobbe et al. BMC Systems Biology 2011 5:165 doi:10.1186/1752-0509-5-165 |
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