Additional file 5.

TCA cycle as represented in each of the five metabolic pathway databases. Adapted version of Figure 2 in the main text for each of the metabolic pathway databases separately. Reactions occurring in the TCA cycle for the selected database are highlighted. Metabolites are represented by rectangles, genes by rounded rectangles, and EC numbers by parallelograms. Color indicates how many of the five databases include a specific entity. Color of an arrow indicates the number of databases that agree upon an entire reaction, i.e., all its metabolites (except H+ which was matched separately). 'x' denotes a missing EC number.

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Stobbe et al. BMC Systems Biology 2011 5:165   doi:10.1186/1752-0509-5-165