Prediction of co-variance. (A) Loadings plot of principal component analysis indicates strong co-variance between Grx1 and Prx2. (B) Off-target "modulation" of Prx2 by variable silencing of Grx1 in epi-allelic cell lines shows co-variance of Grx1 and Prx2 levels in three of four cell lines.
Kippner et al. BMC Systems Biology 2011 5:164 doi:10.1186/1752-0509-5-164