Clustering of Significantly Expressed Transcripts in Glucose (A) or Ammonium (B) Perturbations. The self-organization of the dynamic response of the differentially expressed transcripts around a 2 × 4 arrangement of 8 imaginary points in space in the case of carbon catabolite repression and a 3 × 3 arrangement of 9 imaginary points in space in the case of nitrogen catabolite repression are presented. The cluster number is indicated in the top left corner of each cell. The number of genes in each cluster, which is formed around the imaginary points in space with an acceptable confidence interval, is indicated in the top centre and each red square represents a time point. The blue and yellow curves represent the confidence interval around the centroids.
Dikicioglu et al. BMC Systems Biology 2011 5:148 doi:10.1186/1752-0509-5-148