Resolution:
## Figure 3.
Distribution of . The horizontal axis shows the modularity index M and of the number of modules s for genotypes of phenotype with V= 89 in an ensemble and comparison with _{env }E. coliM in (a) and the number of modules s in (b). The vertical axis shows the frequency of genotypes with the corresponding
value of M (panel a) and s (panel b) in a random sample of 1000 genotypes (n = 831 reactions each, as in the in silico E. coli metabolic model) that are viable in V= 89 different minimal environments. In both panels, the histogram is displayed along
with estimates of _{env }M and s for E. coli. From (a), we can reject at a p-value of 0.028 the hypothesis that the modularity
index M of E. coli is drawn from this same distribution. Thus, E. coli can be considered as atypically modular.
Samal |