Example of a FCS in the E. coli metabolic network. We display a FCS of 12 reactions in the E. coli metabolic network that is branched and contains a cycle. In this figure, the (hyper) edges represent reactions involving metabolites. Green edges represent irreversible reactions and red edges represent reversible reactions. To reduce clutter, the ubiquitous high degree metabolites such as ATP, NADH, etc. have been omitted from this figure. Abbreviations of metabolite names are as follows: 26dap-M = meso-2,6-Diaminoheptanedioate; ala-D = D-Alanine; ala-L = L-Alanine; glu-D = D-Glutamate; glu-L = L-Glutamate; peptido_EC = Peptidoglycan subunit; uaagmda = Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-ala-D-glu-meso-2,6-diaminopimeloyl-D-ala-D-ala; uaccg = UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine; uacgam = UDP-N-acetyl-D-glucosamine; uagmda = Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine; uama = UDP-N-acetylmuramoyl-L-alanine; uamag = UDP-N-acetylmuramoyl-L-alanyl-D-glutamate; uamr = UDP-N-acetylmuramate; udcpdp = Undecaprenyl diphosphate; udcpp = Undecaprenyl phosphate; ugmd = UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminopimelate; ugmda = UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine.
Samal et al. BMC Systems Biology 2011 5:135 doi:10.1186/1752-0509-5-135