Differences between WMI and BMI conservation rates across all pairwise comparison. Green bars and red bars represent conservation statistic for real and random modules respectively. The bars represent the difference between WMI and BMI conservation rates (darker green and red) and the difference between extended WMI and extended BMI conservation rates (brighter green and red). The species are indicated on the vertical axis as follows (c-S.cerevisiae, p-S.pombe, e-C.elegans, f-D.melanogaster). For most data types the improvement for the real networks is very large. In contrast, for random networks the within module edges are usually less conserved when compared to the overall conservation indicating that the within module conservation bias is even stronger.
Zinman et al. BMC Systems Biology 2011 5:134 doi:10.1186/1752-0509-5-134