Predicted biological target processes and pathways. Overview of the predicted biological target processes and pathways obtained from enrichment analysis. Information derived from the chemical structure of the drugs was used to predict possible targets. These possible targets were then used to predict target processes and pathways for rosuvastatin (RSV; orange), fenofibrate (FF; blue) and LXR activator T0901317 (T09; red). A: Target distribution overview demonstrating that each of the drugs has a characteristic target pattern with little overlap between the drugs; B: Most significant common pathway maps for RSV, FF and T09.
Kleemann et al. BMC Systems Biology 2011 5:125 doi:10.1186/1752-0509-5-125