Figure 7.

Retrosynthetic map for the production of paclitaxel (taxol) in yeast. Compounds in gray are endogenous to the chassis organism (S. cerevisiae); enzymatic reactions are represented as circles; 10-deactyl-2-debenzoylbaccatin III appears as a branching compound; the target compound is at the bottom of the plot.

Carbonell et al. BMC Systems Biology 2011 5:122   doi:10.1186/1752-0509-5-122
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