A regulatory network for the genes on the amplified recurrent ICNV regions. The key driver analysis was applied to the genes on the regions and the combined Bayesian network to identify potential key drivers. The largest nodes in the network are the global drivers and the medium size nodes are local drivers while the non-drivers are the smallest nodes. The genes found in the siRNA signature V1 are highlighted in green.
Tran et al. BMC Systems Biology 2011 5:121 doi:10.1186/1752-0509-5-121