Table 1

Summary of the reaction directionality assignments in the model

Number in each group

% of total Reactions


Total Irreversible

401

35

Thermodynamics only

109

9

Heuristics + Thermodynamics

125

11

ABC Transporter/tRNA charging

93

8

Spontaneous

8

1

Others*

66

6

Total Reversible

757

65

Thermodynamics/Heuristics

607

52

Unknown

150

13


Total no. of reactions

1158


* Others includes groups of reactions assigned as irreversible based on SBC analysis or literature (e.g. other databases)

Imam et al. BMC Systems Biology 2011 5:116   doi:10.1186/1752-0509-5-116

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