Sensitivity for gaseous uptake rates of H2 and CO2 on lithoautotrophic growth of R. eutropha. (A) Overview of the CBB cycle for carbon fixation and its overall reaction. (B) Mesh plots graph 3D data as a continuous surface for H2 uptake rate, CO2 uptake rate, and growth rate when the O2 uptake rate is 10 mmol gDCW-1 h-1. For simulation of lithoautotrophic growth, the D-fructose uptake rate was constrained to zero and reactions related with CBB cycle were activated.
Park et al. BMC Systems Biology 2011 5:101 doi:10.1186/1752-0509-5-101