Growth of BioModels Database. Graph depicting the number of models (green) and the number of reactions (yellow) stored in BioModels Database at each release of the database made so far. The number of reactions includes SBML "rate rules", since some models only use rate rules. The graph illustrates that not only has the number of models increased approximately ten-fold since 2005, but the average complexity of those models has nearly tripled in the same period.
Li et al. BMC Systems Biology 2010 4:92 doi:10.1186/1752-0509-4-92