Table 1

Number of genes associated with the listed types of molecular alteration

Genome

Cell line

Clinical


Amplification

25

24

Deletion

5

16

Insertion

2

8

Methylation/Acetylation

18

23

Single Nucleotide Polymorphism

3

21

Transition

14

39

Translocation

3

1

Transversion

16

47

Transcriptome


Expression Level

88

2027

Splice Variant

28

17

Proteome


Activity

8

12

Altered Interaction

16

3

Altered Isoform Splice Variant

10

9

Altered Localisation

9

31

Amino Acid Change

6

31

Deletion

0

2

Expression Level

36

117

Post Translational Modification

13

4


Genes affected by at least one molecular alteration

2238


Mosca et al. BMC Systems Biology 2010 4:76   doi:10.1186/1752-0509-4-76

Open Data