Additional file 6.

Overlay of Ifn-β Regulated Targets onto the Integrated Map of Macrophage Pathways. Components within clusters of co-ordinately expressed transcripts following Ifn-β stimulation were exported as class sets from a mouse expression graph generated in BioLayout Express3D and imported onto the 'human' macrophage pathway diagram (.layout file) within BioLayout Express3D. Pathway components that are regulated by Ifn-β are enlarged and coloured according to their behaviour within the dataset and all other nodes are coloured grey, in this way allowing the easy identification and visualisation of regulated components. BioLayout Express3D software is freely available and can be downloaded at http://www.biolayout.org/ webcite

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Raza et al. BMC Systems Biology 2010 4:63   doi:10.1186/1752-0509-4-63