Catabolic regimes within proliferating mammalian cells. a, b, c, d) Model-predicted (lines) and measured (symbols) fluxes as a function of the glucose uptake rate: a) and b) LS mouse cells, c) hybridoma cells and d) mixture of cancer and normal cells. The two different metabolic regimes are indicated by the white and gray backgrounds, respectively. All fluxes are reported in units of f1, the glucose uptake rate threshold, reported in panel e).
Vazquez et al. BMC Systems Biology 2010 4:58 doi:10.1186/1752-0509-4-58