Table 4 |
||||||||||
|
Experimentally verified targets. |
||||||||||
|
miRNA |
P-value for differential expression of miRNA |
Up or down regulated miRNA |
Gene |
P-value for differential expression of gene |
Up or down regulated gene |
Regression coefficient |
P-value for testing association of miRNA with target mRNA |
Coefficient of determination |
Function of gene |
References |
|
|
||||||||||
|
mir-124a |
8.62E-08 |
Down |
CTDSP1 |
8.4E-07 |
Up |
-17.7 |
2.22E-16 |
0.244 |
[42] |
|
|
mir-155 |
1.31E-07 |
Up |
LDOC1 |
1.67E-07 |
Down |
-197 |
4.00E-15 |
0.223 |
tumor suppressor |
[47] |
|
mir-155 |
1.31E-07 |
Up |
SCAMP1 |
3.27E-06 |
Down |
-30.9 |
6.06E-10 |
0.145 |
[43] |
|
|
mir-16 |
0.0000178 |
Up |
RTN4 |
9.44E-08 |
Down |
-766 |
2.66E-08 |
0.119 |
tumor suppressor |
[43] |
|
mir-16 |
0.0000178 |
Up |
SLC25A22 |
3.36E-08 |
Down |
-37.8 |
1.97E-11 |
0.168 |
[43] |
|
|
mir-16 |
0.0000178 |
Up |
VTI1B |
7.15E-08 |
Down |
-122 |
1.03E-05 |
0.0765 |
[43] |
|
|
mir-21 |
9.98E-08 |
Up |
BASP1 |
2.98E-08 |
Down |
-743 |
0.00E+00 |
0.349 |
[44] |
|
|
mir-21 |
9.98E-08 |
Up |
RTN4 |
9.44E-08 |
Down |
-246 |
1.16E-05 |
0.0756 |
[44] |
|
|
mir-210 |
1.48E-06 |
Up |
EFNA3 |
4.67E-07 |
Down |
-10.4 |
4.61E-05 |
0.0657 |
[48] |
|
|
mir-29b |
2.07E-07 |
Down |
COL4A2 |
1.83E-07 |
Up |
-164 |
8.92E-05 |
0.0609 |
[50] |
|
|
mir-29c |
3.66E-07 |
Down |
COL4A2 |
1.83E-07 |
Up |
-260 |
1.99E-07 |
0.105 |
[49] |
|
|
mir-29c |
3.66E-07 |
Down |
COL4A1 |
4.91E-08 |
Up |
-389 |
1.35E-08 |
0.124 |
[49] |
|
|
mir-29c |
3.66E-07 |
Down |
TDG |
5.21E-07 |
Up |
-95.5 |
3.22E-14 |
0.21 |
[49] |
|
|
mir-33 |
9.6317E-06 |
Down |
ABCA1 |
1.0396E-06 |
Up |
-114.5 |
5.941E-12 |
0.176 |
[51] |
|
|
|
||||||||||
|
Dong et al. BMC Systems Biology 2010 4:163 doi:10.1186/1752-0509-4-163 |
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