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Open Access Highly Accessed Research article

The zipper mechanism in phagocytosis: energetic requirements and variability in phagocytic cup shape

Sylvain Tollis12, Anna E Dart23, George Tzircotis23 and Robert G Endres12*

Author Affiliations

1 Division of Molecular Biosciences, South Kensington Campus, Imperial College London, SW72AZ London, UK

2 Centre for Integrative Systems Biology at Imperial College (CISBIC), South Kensington Campus, Imperial College London, SW72AZ London, UK

3 Division of Cell and Molecular Biology, South Kensington Campus, Imperial College London, SW72AZ London, UK

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BMC Systems Biology 2010, 4:149  doi:10.1186/1752-0509-4-149

Published: 8 November 2010

Additional files

Additional file 1:

Supplementary information. The supplementary information file contains additional discussion on parameter values in simulations, as well as additional simulation results and fluorescence images analysis. It includes 10 supplementary figures, each accompanied by a short descriptive paragraph.

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Open Data

Additional file 2:

Simulation movie. This file shows a 3D simulation of phagocytic engulfment.

Format: AVI Size: 523KB Download file

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Open Data