Table 2

Interactions predicted by C3NET, shown as red edges in Fig. 7, declared as false positives according to the reference network <a onClick="popup('http://www.biomedcentral.com/1752-0509/4/132/mathml/M14','MathML',630,470);return false;" target="_blank" href="http://www.biomedcentral.com/1752-0509/4/132/mathml/M14">View MathML</a>.

regulator gene

regulated gene

literature


confirmed

gadE

gadB

[49]

gadE

hdeD

[49]

gadE

yhiD

[50]

lrp

pntA

[51]

fliA

tsr

[52]

flhD

flhC

[53] (protein complex)


predicted interactions

dnaA

amiB

dnaA

rnpA

fliA

flgA

lrp

artJ

lrp

aroP

indirect interaction via TyrR [47]

lexA

araB

lexA

araD

lexA

araE

lrp

pntB

tdcR

yiaM

tdcR

bglG

csgD

trpD

csgD

trpC

zur

glmU

purR

aroH

fnr

dinF

cbl

treB

gadE

slp

gadE

dps


Among these 25 interactions 6 receive support from the literature to be in fact true positives.

Altay and Emmert-Streib BMC Systems Biology 2010 4:132   doi:10.1186/1752-0509-4-132

Open Data