BMC Systems Biology

official impact factor 3.57

Open Access Research article

Integrative inference of gene-regulatory networks in Escherichia coli using information theoretic concepts and sequence analysis

Christoph Kaleta1,2*, Anna Göhler3, Stefan Schuster2, Knut Jahreis3, Reinhard Guthke1 and Swetlana Nikolajewa1

Author Affiliations

1 Systems Biology/Bioinformatics Group, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute, Beutenbergstr. 11a, D-07745 Jena, Germany

2 Dept. of Bioinformatics, Friedrich-Schiller-University Jena, Ernst-Abbe-Platz 2, D-07743 Jena, Germany

3 Dept. of Genetics, University of Osnabrück, Barbarastraße 11, D-49076 Osnabrück, Germany

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BMC Systems Biology 2010, 4:116 doi:10.1186/1752-0509-4-116

Published: 18 August 2010

Additional files

Additional file 1:

Supplementary Material. Supplemental Material containing further information on the inference procedure and the inferred interactions.

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Open Data

Additional file 2:

DTInfer. R-package for the inference of gene-regulatory networks from microarray data using directed information and mutual information

Format: GZ Size: 15KB Download file

Open Data