Resolution:
## Figure 2.
Histogram of . Histogram of X_{1 }in the Reversible isomerisation reactionX_{1 }in the Reversible isomerisation reaction (10^{6 }samples used) solved by the SSA (grey background), Poisson τ-leap (dashed line), and optimal RK τ-leap methods with bounded relative variance. (a) τ = 0.05 (z = -1), Optimal RK τ-leap s = 3, ϵ = 0.1 (solid line) and s = 5, ϵ = 0.1 ("+" marks), (b) τ = 0.4 (z = -8), Optimal RK τ-leap s = 3, ϵ = 0.5 (solid line) and s = 5, ϵ = 0.1 ("+" marks), Poisson τ-leap is unstable for this time step. (c) τ = 0.6 (z = -12), Optimal RK τ-leap s = 5, ϵ = 0.5 ("+" marks), Poisson τ-leap and Optimal RK τ-leap s = 3 are unstable for this time step.
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