Classification model that discriminates up- and down-regulated TGF-β/SMAD targets and corresponding SMAD co-regulatory modules. Upper panel shows the CART model that discriminates between the TGF-β/SMAD up- and down-regulated targets. Lower panel shows the derived cis-regulatory modules of these target genes identified by the CART model. In the CART trees, "yes" means the TFBS was present and "no" means the TFBS was absent.
Qin et al. BMC Systems Biology 2009 3:73 doi:10.1186/1752-0509-3-73