Table 2

95%-confidence intervals of the parameters in the reference scenario

Variable

95%-confidence interval

Unit

ka

[5.0, 8.5]

(μM·s)^-1

ki

[0.0025, 0.0042]

s^-1

kp

[0.095, 0.095]

s^-1

kdp

[0.00060, 0.0011]

s^-1

kuv

[0.00016, 0.00032]

s^-1

IKKscale

[0.78, 1.2]

^-

Confidence intervals were obtained by fitting to perturbed experimental data and determining the 2.5% and 97.5% quantiles of the resulting parameter sets, as described in the Methods section.

Witt et al. BMC Systems Biology 2009 3:71   doi:10.1186/1752-0509-3-71