Table 4

Over-represented CREs for 4 significant N/H-biclusters.

CRE Name

P-value (N/H-Bicluster vs. N-bicluster 9 Exclusive)

% Present in N/H-bicluster Genes

% Present in N-bicluster 9 Exclusive Genes

% Present in N-bicluster 9 Genes


E2F

0.0022**

60.5%

27.08%

40.48%

HSE

0.0089**

60.5%

31.25%

42.06%


Results of a promoter sequence analysis of genes from 4 significant N/H biclusters based on ANOVA with the Fisher Exact Test used to determine CRE frequency over-representation of in the collective gene list (38 genes) vs. N-bicluster 9 exclusive genes. Indicated in this table are the p-values for over-representation, the frequency of these CREs in the 4 N/H biclusters, the frequency of the same CREs in the N-bicluster 9 exclusive gene list and the frequency of these CREs in the full N-bicluster 9 gene list. Based on the analysis of the 4 significant N/H-biclusters, only the p-values for the HSE and E2F CREs were significant, indicating over-representation of these CREs (significance based on a 5% FDR cutoff). **P-values 0.001–0.01

Nero et al. BMC Systems Biology 2009 3:59   doi:10.1186/1752-0509-3-59

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