Table 1

Global gene expression datasets utilized for validation of metabolic syndrome and neuropsychiatric subnetworks

METABOLIC SYNDROME


Condition

Species

Tissue

GEO Acc.

Reference


obese/lean

Human

adipocytes

GSE2508

[30]

obese/lean

Mouse

adipocytes

GSE4692

[31]

Familial combined hyperlipedemia

Human

monocytes

GSE11393

[32]

Treatment

Species

Tissue

GEO Acc.

Reference


Fenofibrate

Rat

liver

GSE8251

[33]

4-hydroxyphenylretinamide

Rat

liver

GSE3952

[34]

9-cis retinoic acid

Rat

liver

GSE3952

[34]

Targretin

Rat

liver

GSE3952

[34]

Vitamin A deficient diet

Rat

liver

GSE1600

[35]

Omega 3 fatty acids

Rat

cardiomyocytes

GSE4327

[36]

Thiazolidinediones

Human

3T3-L1 adipocytes

GSE1458

[37]

Atorvastatin

Human

monocytes

GSE11393

[32]

Cyfluthrin

Human

astrocytes

GSE5023

[38]

NEUROPSYCHIATRIC DISORDERS


Condition

Species

Tissue

GEO/EBI Acc.

Reference


Bipolar Disorder

Human

prefrontal cortex

GSE12654

[39]

Depression

Human

prefrontal cortex

GSE12654

[39]

Schizophrenia

Human

prefrontal cortex

GSE12654

[39]

Schizophrenia

Human

frontal cortex

E-MEXP-857

[40]

Anxiety

Mouse

various brain regions

GSE3327

[41]

Autism

Human

lymphoblastoid cell lines

GSE7329

[42]

Autism

Human

whole blood

GSE6575

[43]

Treatment

Species

Tissue

GEO Acc.

Reference


Chlorpyrifos

Human

astrocytes

GSE5023

[38]

Chlorpyrifos

Rat

forebrain

GSE9751

[44]


Gohlke et al. BMC Systems Biology 2009 3:46   doi:10.1186/1752-0509-3-46

Open Data