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Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo

Jesse J Smith, Renée Deehan Kenney, David J Gagne, Brian P Frushour, William Ladd, Heidi L Galonek, Kristine Israelian, Jeffrey Song, Giedre Razvadauskaite, Amy V Lynch, David P Carney, Robin J Johnson, Siva Lavu, Andre Iffland, Peter J Elliott, Philip D Lambert, Keith O Elliston, Michael R Jirousek, Jill C Milne and Olivier Boss*

BMC Systems Biology 2009, 3:31  doi:10.1186/1752-0509-3-31