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Open Access Research article

A computational approach to resolve cell level contributions to early glandular epithelial cancer progression

Sean HJ Kim1, Jayanta Debnath2, Keith Mostov3, Sunwoo Park4 and C Anthony Hunt14*

Author Affiliations

1 UCSF/UC Berkeley Joint Graduate Group in Bioengineering, University of California, Berkeley, California, 94720, USA

2 Department of Pathology, University of California, San Francisco, California 94143, USA

3 Department of Anatomy, University of California, San Francisco, California 94143, USA

4 Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, California 94143, USA

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BMC Systems Biology 2009, 3:122  doi:10.1186/1752-0509-3-122

Published: 31 December 2009

Additional files

Additional file 1:

Supplementary Material. Provided are detailed descriptions of ISEA morphology index, ISEA CELL axiom use patterns following Axiom 5 or 6 dysregulation, and a diagram illustrating model refinement and cross-model validation.

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