BMC Systems Biology

official impact factor 3.57

Open Access Highly Access Research article

Flux Design: In silico design of cell factories based on correlation of pathway fluxes to desired properties

Guido Melzer, Manely E Esfandabadi, Ezequiel Franco-Lara and Christoph Wittmann*

Author Affiliations

Institute of Biochemical Engineering, Technische Universität Braunschweig, Gaußstr 17, 38106 Braunschweig, Germany

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BMC Systems Biology 2009, 3:120 doi:10.1186/1752-0509-3-120

Published: 25 December 2009

Additional files

Additional file 1:

Scenario Escherichia coli. Small example network model of E. coli for succinyl-CoA production, results of the target validity calculation and statistical evaluation.

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Additional file 2:

Scenario Corynebacterium glutamicum. Metabolic network model of C. glutamicum, results of the target validity calculation and statistical evaluation.

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Additional file 3:

Scenario Aspergillus niger. Metabolic network model of A. niger, results of the target validity calculation and statistical evaluation.

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