BMC Systems Biology

official impact factor 3.57

Open Access Research article

In silico approaches to study mass and energy flows in microbial consortia: a syntrophic case study

Reed Taffs1,2, John E Aston1,2, Kristen Brileya1,2, Zackary Jay1, Christian G Klatt1, Shawn McGlynn1, Natasha Mallette1,2, Scott Montross1, Robin Gerlach1,2, William P Inskeep1, David M Ward1 and Ross P Carlson1,2*

Author Affiliations

1 Thermal Biology Institute, Montana State University, Bozeman, MT 59717, USA

2 Center for Biofilm Engineering, Montana State University, Bozeman, MT 59717, USA

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BMC Systems Biology 2009, 3:114 doi:10.1186/1752-0509-3-114

Published: 10 December 2009

Additional files

Additional file 1:

Supplement. This spreadsheet contains all additional information referenced in the text. This material includes the criteria used to select modes during the first round of processing for the nested models, a short illustration of the mechanisms used to separate metabolites by guild for the modeling methods, the script used to normalize first-round vectors for the nested approach, the full error results from the nested models, a sample calculation illustrating how modes were combined in the daytime case study, and the final models used to produce all discussed results (along with diagrams of the individual and pooled metabolic networks). Final network models will be submitted in SBML format to the BioModels database http://www.ebi.ac.uk/biomodels-main/ webcite upon manuscript publication.

Format: XLS Size: 4MB Download file

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