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Open Access Methodology article

Exact model reduction of combinatorial reaction networks

Holger Conzelmann1*, Dirk Fey2 and Ernst D Gilles1

Author Affiliations

1 Max-Planck Institute for Dynamics of Complex Technical Systems, Sandtorstr. 1, 39106, Magdeburg, Germany

2 Industrial Control Centre, Department of Electronic & Electrical Engineering, University of Strathclyde, Glasgow, Scotland, UK

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BMC Systems Biology 2008, 2:78 doi:10.1186/1752-0509-2-78

Published: 28 August 2008

Additional files

Additional file 1:

Matlab simulation files for the complete 5,182 ODE model of EGF and insulin receptor crosstalk.

Format: ZIP Size: 1.8MB Download file

Open Data

Additional file 2:

ALC input file to generate an exactly reduced version of the EGF and insulin receptor model.

Format: TXT Size: 7KB Download file

Open Data

Additional file 3:

Transformation of the ALC generated model according to the proposed approach and subsequent elimination of redundant information.

Format: NB Size: 418KB Download file

Open Data

Additional file 4:

Matlab simulation file for the reduced ODE model of EGF and insulin receptor crosstalk.

Format: M Size: 37KB Download file

Open Data