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Open Access Highly Accessed Review

A review of imaging techniques for systems biology

Armen R Kherlopian, Ting Song, Qi Duan, Mathew A Neimark, Ming J Po, John K Gohagan and Andrew F Laine*

BMC Systems Biology 2008, 2:74  doi:10.1186/1752-0509-2-74

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What ever happened to single photon scintigraphy?

Lionel Zuckier   (2009-02-05 16:25)  New Jersey Medical School email

Very interesting and comprehensive article. Nonetheless, I was surprised by the complete omission of single-photon imaging, both planar and tomographic. These are powerful techniques with resolution in small animals, such as by microSPECT, superior to that of dual-photon (PET)imaging (though lacking absolute quantification as in PET). These techniques have been used for decades to provide much basic physiologic information by way of imaging and compartmental modeling.

Competing interests



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