Figure 8.

pH dependence of Ca2+ binding to CaM. Ca2+ binding to CaM under different pH conditions measured by [9] can be explained in terms of altered dissociation and cooperative dissociation constants. The increase of pH raises affinity to Ca2+ and eliminates cooperativity between Ca2+ binding sites on CaM.

Valeyev et al. BMC Systems Biology 2008 2:48   doi:10.1186/1752-0509-2-48
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