The kinetic scheme for the non-cooperative model. Model 1: This simplified model is based on the assumption that all Ca2+ molecules are independent of each other and of interactions with a target protein. The relative simplicity of the model allows a straightforward description of CaM-dependent target protein regulation and lays the groundwork for a more complete understanding of cooperative- and target interaction-dependent effects.
Valeyev et al. BMC Systems Biology 2008 2:48 doi:10.1186/1752-0509-2-48