BMC Systems Biology

official impact factor 3.57

Open Access Research article

One hub-one process: a tool based view on regulatory network topology

Jacob B Axelsen1, Sebastian Bernhardsson2 and Kim Sneppen3*

Author Affiliations

1 Centro de Astrobiología, Instituto Nacional de Técnica Aeroespacial, Ctra de Ajalvir km 4, 28850 Torrejón de Ardoz, Madrid, Spain

2 Department of Theoretical Physics, Umeå University, 901 87 Umeå, Sweden

3 Center for Models of Life, Niels Bohr Institute, Blegdamsvej 17 DK-2100 Copenhagen Ø, Denmark

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BMC Systems Biology 2008, 2:25 doi:10.1186/1752-0509-2-25

Published: 4 March 2008

Additional files

Additional file 1:

Correlating microarray data of stress conditions with the YPD. Using 465 microarrays of stress conditions for S. Cerevisiae, from Stanford Genome Database, we perform a statistical analysis showing that functions are localized in the regulatory network.

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