Results of intracellular signalling model. Model predictions – effect of cell contact stability on Erk-PP. Case 1, two cells make an initial small contact of 2 μm, which increases linearly to 23 μm over 6 hours. Case 2 shows the same initial formation pattern, but with an instantaneous break of contact after 4 hours when it has reached 16 μm length. Case 3 shows the signal arising from an 'instantaneously' formed 12 μm contact.
Walker et al. BMC Systems Biology 2008 2:102 doi:10.1186/1752-0509-2-102