Email updates

Keep up to date with the latest news and content from BMC Systems Biology and BioMed Central.

Open Access Research article

From pathway to population – a multiscale model of juxtacrine EGFR-MAPK signalling

DC Walker1*, NT Georgopoulos2 and J Southgate2

Author Affiliations

1 Department of Computer Science, University of Sheffield, Kroto Research Institute, North Campus, Broad Lane, Sheffield, S3 7HQ, UK

2 Jack Birch Unit of Molecular Carcinogenesis, Department of Biology, University of York, York YO10 5YW, UK

For all author emails, please log on.

BMC Systems Biology 2008, 2:102  doi:10.1186/1752-0509-2-102

Published: 26 November 2008

Additional files

Additional file 1:

Time lapse movie of cultured low density urothelial cells in low (0.09 mM) calcium – recording frame rate = 1 frame per minute.

Format: AVI Size: 10.9MB Download file

Playing the movie within this page requires QuickTime 3 or later and JavaScript. Read more

Open Data

Additional file 2:

Time lapse movie of cultured high density urothelial cells in low (0.09 mM) calcium – recording frame rate = 1 frame per 10 minutes.

Format: AVI Size: 11.2MB Download file

Playing the movie within this page requires QuickTime 3 or later and JavaScript. Read more

Open Data

Additional file 3:

Virtual time lapse movie of agent simulation in a low calcium (0.1 mM) environment. Circles represent agents (cells) and red lines represent E-cadherin mediated contacts. 1 frame = 30 minutes.

Format: AVI Size: 16.4MB Download file

Playing the movie within this page requires QuickTime 3 or later and JavaScript. Read more

Open Data

Additional file 4:

Virtual time lapse movie of agent simulation in a physiological calcium (2.0 mM) environment. Circles represent agents (cells) and red lines represent E-cadherin mediated contacts. 1 frame = 30 minutes.

Format: AVI Size: 16.8MB Download file

Playing the movie within this page requires QuickTime 3 or later and JavaScript. Read more

Open Data