Research article
Modeling protein network evolution under genome duplication and domain shuffling
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* Corresponding author: Hervé Isambert herve.isambert@curie.fr
RNA dynamics and Biomolecular Systems Lab, CNRS UMR168, Institut Curie, Section de Recherche, 11 rue P. & M. Curie, 75005 Paris, France
BMC Systems Biology 2007, 1:49 doi:10.1186/1752-0509-1-49
Published: 13 November 2007Additional files
Additional File 1:
Supporting Information (6 pages). I. Model of PPI network evolution under WGD with symmetric divergence and link "complementation". II. Proof of Functional Recurrences (Eq. 8 and Eq. S1). III. Gene functionalization patterns in different models of PPI network evolution under WGD. IV. Statistical weighting of indirect interactions from protein complexes. V. Evolution of PPI networks including self-interacting proteins under WGD.
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