Open Access Case report

Magnetic resonance imaging and genetic investigation of a case of rottweiler leukoencephalomyelopathy

Katrin Hirschvogel1, Kaspar Matiasek2, Katharina Flatz3, Michaela Drögemüller4, Cord Drögemüller4, Bärbel Reiner2 and Andrea Fischer1*

Author Affiliations

1 Department of Veterinary Clinical Sciences Ludwig-Maximilians-Universitaet, Neurology Service, Clinic of Small Animal Medicine, Munich, Germany

2 Department of Veterinary Clinical Sciences Ludwig-Maximilians-Universitaet, Section of Clinical & Comparative Neuropathology, Institute of Veterinary Pathology, Munich, Germany

3 Department of Veterinary Clinical Sciences Ludwig-Maximilians-Universitaet, Clinic of Small Animal Surgery and Reproduction, Munich, Germany; Small Animal Hospital Hüttig, Reutlingen, Germany

4 Institute of Genetics, Vetsuisse Faculty, University of Berne, Berne, Switzerland

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BMC Veterinary Research 2013, 9:57  doi:10.1186/1746-6148-9-57

Published: 26 March 2013

Additional files

Additional file 1:

Movie of a Rottweiler with confirmed leukoencephalomyelopathy. The movie shows the severe generalised ataxia with hypermetria of the thoracic (with prolonged protraction, overreaching action and limb extension) and pelvic limbs. The postural reactions were delayed, and the thoracic limbs were more severely affected than the pelvic limbs.

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Open Data

Additional file 2:

Sequencing methods and primers.

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Open Data