Additional file 1.
Smoothing curves for non-linear relationships. Estimated smoothing curves of the non-linear parameters of the effect of time on pulse rate (PR) and arterial haemoglobin saturation (SpO2), as well as the effect of SpO2 on PR and respiratory rate (fr) determined by a series of generalized additive mixed effects models (GAMMs). Dashed lines represent 95% CI. Significant non-linear relationships occurred for PR (P ≤ 0.0001) and SpO2 (P < 0.0001) as a smoothing function of time, as well as PR (P ≤ 0.0001) and fr (P < 0.0001) as a smoothing function of SpO2.
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Burnside et al. BMC Veterinary Research 2013 9:48 doi:10.1186/1746-6148-9-48