Table 3

Concentration of signalling proteins in different disease categories
SRMA SRMA R SRMA Th Syst Inflam ME CNS-Mix IE Healthy
IL-6 CSF 1582 637.7 0 0 3 0 0 3
(pg/mL) (163.1-3473) (17.19-1507) (0–1.5) (0–31.25) (0–175.6) (0–3) (0–3) (0.75-3)
Serum 3 17.13 0 17.13 0 0 1.5 3
(pg/mL) (3–124) (3–36.24) (0–0) (0–77.1) (0–3) (0–3) (0–3) (0–3)
VEGF CSF 36.31 20.80 0 0 0 0 0 0
(pg/mL) (1–175.2) (0–69.96) (0–0) (0–0) (0–65.71) (0–0) (0–0) (0–0)
Serum 43.92 33.71 3.9 3.9 0 0 0 3.9
(pg/mL) (3.9-94.5) (0.98-42.9) (0–3.9) (3.9-57.8) (0–3.9) (0–3.9) (0–0) (1.95-3.9)
TGF-β1 CSF 90 n.a. n.a. n.a. 58 0 n.a. 0
(pg/mL) (0–429) (0–214) (0–95) (0–0)
Serum 13.57 n.a. n.a. n.a. 22.84 19.31 n.a. 23.84
(ng/mL) (9.93-19.27) (11.86-27.96) (14.77-23.25) (18.19-29.16)

IL-6: interleukin-6; VEGF: vascular endothelial grow factor; TGF-β1: Transforming growth factor beta; CSF: cerebrospinal fluid; CNS: central nervous system; SRMA: steroid-responsive meningitis-arteritis; Syst Inflam: systemic inflammatory diseases; ME: other inflammatory CNS diseases; CNS-Mix: miscellaneous non-inflammatory CNS diseases; IE: idiopathic epilepsy; n.a.: not available. Data are given as median and range (25th–75th percentile).

Maiolini et al.

Maiolini et al. BMC Veterinary Research 2013 9:23   doi:10.1186/1746-6148-9-23

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