Immunohistochemistry for neurofilaments. Sections of the cerebral cortex from a control (a) and a lissencephalic (b) brain, taken at the same magnification and immunolabelled for neurofilaments. In the control brain, the typical layering of this area (I to VI) can be seen, where the neurons from the pyramidal layers show the strongest signal. In the lissencephalic brain, three different layers can be identified according to neurofilament expression. Immunoperoxidase staining for neurofilaments.
Pérez et al. BMC Veterinary Research 2013 9:156 doi:10.1186/1746-6148-9-156