Table 1

Details of 9 horses treated with CXL and medical treatment for stromal ulcerative keratitis
Horse Breed Sex and age Disease history Topical medication pre CXL Stromal ulcer size; depth pre CXL Stromal melting Comments Microbes on cytology and in culture pre CXL Fluor. neg. post CXL Follow up time
1 Mixed breed pony G 6 yr 4 w Fucidic acid 1 w, chloramphenicol 2 w, natamycin 1 w 5 × 5 mm; 1/3 no Hypopyon Abundant fungal hyphae/ Yeast overgrowth, mixed bacteria Enucl. n/a
2 Swedish Warmblood G 5 yr 4½ w Fucidic acid 1 w, chloramphenicol-ciprofloxacin 2½ w, natamycin 1 w 4 × 4 mm; 1/3 7 × 7 mm; 1/3 yes Abundant fungal hyphae/ Scedosporium spp. 9 d 19 mo
3 Warmblood Trotter F 1 yr 1 w Chloramphenicol 1 w 10 × 10 mm; 2/3 yes Extensive cellular infiltration. Severe purulent discharge Abundant coccoid bacteria/ ß-hem. Streptococcus 20 d 12 mo
4 Islandic horse S 2 yr < 1 w Chloramphenicol < 1w 8 × 8 mm; 2/3 no Hypopyon Sparse coccoid bacteria/ ß-hem. Streptococcus 9 d 11 mo
5 Mixed breed pony F 5 yr > 2 w Fucidic acid >1 w, chloramphenicol + autologous serum in EDTA 1 w 4 × 4 mm; 1/3 5 × 5 mm; 2/3 no Two stromal ulcers in large superficial ulcer. Severe purulent discharge No bacteria/ No growth 9 d + 16 d 9 mo
6 Miniatur Shetland Pony F 16 y < 1 w Fucidic acid < 1 w 8 × 8 mm; 2/3 no Stromal ulcer in large superficial ulcer Abundant bacteria/ Untyped G + bacteria 14 d 6 mo
7 Warmblood Trotter F 1 mo < 1 w No 10 × 13 mm; 2/3 yes Extensive cellular infiltration. Severe purulent discharge Abundant bacteria/ Pasteurella spp 4 d 5 mo
8 Welsh Pony S 2 mo 1 w Chloramphenicol 1 w 5 × 5 mm; 2/3 no Moderate bacteria/ Untyped G + coccoid 14 d 5 mo
9 Welsh Pony F 15 yr 1 d No 6 × 18 mm; 1/3 yes Corneal laceration No bacteria/ No growth 26 d 5 mo

F = female (mare), G = gelding, S = stallion, d = days, mo = months, w = weeks, yr = years, 1/3 = anterior third of the cornea, 2/3 = middle third of the cornea, G + =Gram-positive, ß-hem = ß-hemolytic, enucl = enucleated, n/a = not applicable. All horses were affected unilaterally. For horse no 5, the number of days to fluorescein negativity is listed for each of the two stromal ulcers respectively.

Hellander-Edman et al.

Hellander-Edman et al. BMC Veterinary Research 2013 9:128   doi:10.1186/1746-6148-9-128

Open Data