Table 4

Prognostic factors significantly associated with disease free survival
Variable Univariate Multivariable*
Hazard ratio 95% CI P Hazard ratio 95% CI P
Tumour size
< 3 cm Referent
≥ 3 cm 2.33 1.06-5.14 0.036 NS
Mode of growth
Expansive Referent
Invasive 5.62 1.33-23.80 0.019 NS
MIB1 L.I. (%)
< 40 Referent Referent
≥ 40 4.15 1.74-9.90 0.001 3.24 1.35-7.78 0.009
uPA (%)
< 10 Referent
≥ 10 3.82 1.14-12.72 0.029 NS
MMP-9 (%)
< 50 Referent Referent
≥ 50 4.34 1.93-9.77 <0.001 3.38 1.49-7.67 0.004

*Cox regression model: forward stepwise method – likelihood ratio.

NS - not significant.

Santos et al.

Santos et al. BMC Veterinary Research 2013 9:1   doi:10.1186/1746-6148-9-1

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