Table 1

Down- or up-regulated proteins after 24 hours masitinib treatment
Spot Identified protein AV p-value accession no. in NCBI MW [Da]§ pI§ MOWSE score assigned peptides sequ. cov. [%]
Down-regulated proteins
1 TARDBP −1.52 0.012 gi|6678271 (Ho) 45053 5.85 53 1* 4*
2 EIF3 −1.30 0.014 gi|73974369 (Ca) 29504 7.78 92 8 21
3 ACTR2 −1.09 0.0054 gi|73969816 (Ca) 36488 8.21 46 1* 4*
Up-regulated proteins
4 ANXA1 +1.66 0.0087 gi|73946797 (Ca) 38887 5.84 91 12 31
5 CAPG +1.66 0.0039 gi|73980918 (Ca) 39088 6.04 85 6 24

§The listed molecular weights and pI values correspond to the listed accession numbers, which sometimes belong to species other than Canis familiaris (Ca.).

*These proteins were identified by unique peptide sequences determined by MALDI-TOF MS/MS experiments.

Abbreviations: EIF3: eukaryotic translation initiation factor 3; ACTR2: actin-related protein 2; ANXA1: annexin A1; MCP: Macrophage capping protein; Ca: Canis familiaris; Ho: Homo sapiens.

Klopfleisch et al.

Klopfleisch et al. BMC Veterinary Research 2012 8:96   doi:10.1186/1746-6148-8-96

Open Data