Table 1 |
|||||||||
| List of individual respiratory disease scores in the control and challenge group | |||||||||
| CT score | radiographic score | clinical score* | lung lesion score | App reisolation | |||||
| pig | day 7 | day 21 | day 7 | day 21 | day 7 | day 21 | day 21 | day 21 | |
| control group | 1 | 0.00 | 0.00 | 0.00 | 0.00 | 0.30 | 0.50 | 0.00 | − |
| 2 | 0.00 | 0.21 | 2.00 | 1.00 | 0.72 | 0.10 | 7.04 | − | |
| 3 | 0.00 | 0.00 | 0.00 | 0.00 | 0.50 | 0.20 | 3.57 | − | |
| 4 | 0.00 | 0.00 | 1.00 | 1.00 | 0.60 | 0.70 | 0.00 | − | |
| 5 | 1.30 | 0.29 | 3.00 | 3.00 | 0.53 | 0.30 | 3.57 | − | |
| median | 0.00 | 0.00 | 1.00 | 1.00 | 0.53 | 0.30 | 3.57 | ||
| mean | 0.26 | 0.10 | 1.20 | 1.00 | 0.53 | 0.36 | 2.84 | ||
| SD | 0.58 | 0.14 | 1.30 | 1.22 | 0.15 | 0.24 | 2.95 | ||
| challenge group | 6 | 0.00 | 0.00 | 1.00 | 2.00 | 0.40 | 1.30 | 0.00 | − |
| 7 | 0.00 | 0.00 | 3.00 | 2.00 | 0.90 | 1.00 | 0.00 | − | |
| 8 | 1.10 | 1.10 | 16.00 | 16.00 | 3.07 | 0.81 | 6.32 | + | |
| 91 | 5.20 | 36.00 | 19.10 | 31.431 | +1 | ||||
| 102 | 6.92 | 32.00 | 26.90 | 20.002 | +2 | ||||
| 11 | 2.70 | 1.60 | 12.00 | 14.00 | 2.60 | 2.06 | 4.39 | + | |
| 12 | 2.97 | 2.21 | 15.00 | 12.00 | 2.80 | 1.03 | 6.35 | + | |
| 13 | 3.21 | 2.23 | 21.00 | 25.00 | 2.80 | 0.89 | 12.33 | + | |
| 14 | 0.00 | 0.00 | 2.00 | 2.00 | 0.60 | 0.60 | 0.00 | − | |
| 15 | 0.00 | 0.23 | 4.00 | 1.00 | 1.33 | 0.70 | 0.00 | − | |
| 16 | 1.34 | 1.07 | 12.00 | 11.00 | 2.26 | 0.73 | 5.40 | + | |
| 17 | 1.35 | 0.24 | 5.00 | 10.00 | 1.12 | 0.93 | 1.84 | + | |
| 18 | 2.05 | 3.71 | 26.00 | 23.00 | 1.96 | 2.98 | 21.65 | + | |
| 19 | 2.38 | 1.21 | 24.00 | 22.00 | 1.36 | 2.81 | 3.42 | + | |
| 20 | 2.45 | 1.39 | 13.00 | 10.00 | 1.89 | 0.70 | 3.00 | + | |
| 21 | 2.80 | 1.98 | 14.00 | 4.00 | 1.63 | 1.03 | 5.13 | + | |
| 22 | 0.00 | 0.00 | 10.00 | 12.00 | 0.60 | 1.90 | 0.00 | − | |
| 23 | 0.88 | 1.48 | 4.00 | 7.00 | 1.70 | 2.27 | 2.63 | + | |
| 24 | 1.23 | 0.00 | 4.00 | 8.00 | 0.50 | 1.80 | 0.00 | + | |
| 25 | 1.34 | 0.61 | 9.00 | 8.00 | 0.90 | 2.10 | 1.60 | + | |
| 26 | 2.15 | 1.79 | 26.00 | 15.00 | 2.57 | 1.87 | 8.46 | + | |
| 27 | 3.34 | 1.39 | 7.00 | 7.00 | 2.07 | 1.90 | 5.20 | + | |
| 28 | 0.30 | 0.00 | 10.00 | 15.00 | 0.70 | 1.60 | 0.00 | + | |
| 29 | 0.00 | 0.00 | 10.00 | 9.00 | 0.90 | 1.70 | 0.00 | − | |
| mean | 1.82 | 1.01 | 13.17 | 10.68 | 3.36 | 1.49 | 5.80 | ||
| SD | 1.75 | 1.00 | 9.73 | 6.81 | 6.21 | 0.70 | 8.05 | ||
*Quantification of clinical signs by scoring system of Höltig et al. (2008). Day 7: not affected 0–0.7, slightly affected 0.71–7.13, moderately affected 7.14–13.56, severely affected >13.56. Day 21: not affected 0–2, slightly affected 2.01–34.70, moderately affected 34.71–67.3, severely affected >67.3.
1 day 3 post challenge (euthanized on day 3 post challenge), 2 day 1 post challenge (euthanized on day 1 post challenge), SD standard deviation.
Brauer et al. BMC Veterinary Research 2012 8:47 doi:10.1186/1746-6148-8-47
