Body weight gain (A), Body temperatures (B) and clinical scores (C) in experimentally infected groups. Course of the body weight gain (Figure 1A), body temperature (Figure 1B) and clinical scores (Figure 1C) were recorded in experimental groups of three weeks old, colostrum-deprived piglets inoculated with either a combination of PCV2 and PRRSV (PCV2/PRRSV), PCV2 and PPV (PCV2/PPV), or phosphate buffered saline (controls). For each experimental group consisting of eight (PCV2/PPV) or nine animals (PCV2/PRRSV, controls) data were collected for a period of 26 days post inoculation. Rectal temperatures were measured twice daily and clinical scores were determined based on a collection of predefined clinical symptoms ranging from no disease (0) to severe disease (3). Arrows (↑) indicate time of sampling for SELDI-TOF protein profiling.
Koene et al. BMC Veterinary Research 2012 8:32 doi:10.1186/1746-6148-8-32