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CXCR4 expression in feline mammary carcinoma cells: evidence of a proliferative role for the SDF-1/CXCR4 axis

Angelo Ferrari1, Claudio Petterino1, Alessandra Ratto1, Chiara Campanella1, Roberto Wurth2, Stefano Thellung2, Guendalina Vito1, Federica Barbieri2 and Tullio Florio2*

Author Affiliations

1 Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D'Aosta, National Reference Center of Veterinary and Comparative Oncology (CEROVEC), Piazza Borgo Pila, 16129 Genova, Italy

2 Section of Pharmacology, Department of Internal Medicine, and Centre of Excellence for Biomedical Research, University of Genova, Viale Benedetto XV 2, 16132 Genova, Italy

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BMC Veterinary Research 2012, 8:27  doi:10.1186/1746-6148-8-27

Published: 14 March 2012

Additional files

Additional file 1:

Figure S1 Immunohistochemical controls for CXCR4 expression in feline mammary carcinomas. A. Negative control obtained by omitting the rabbit primary antibody against CXCR4. B. Negative control obtained by substituting the primary antibody with rabbit IgG. C. CXCR4 staining with rabbit anti-CXCR4 antibody (Sigma-Aldrich). D. CXCR4 staining with rabbit anti-CXCR4 antibody (R&D Systems). Tissue images derived from a tubulopapillary carcinoma, bar = 25 microm, original magnification 40×.

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