|Amplification of experimental and natural strains of ovine prion diseases|
|SSBP1 (n = 1)||VRQ||+||-||ND|
|Dawson (n = 1)||VRQ||+||-||ND|
|MRI Suffolk (n = 3)||ARQ||−/−/−||+/−/−||ND|
|Atypical scrapie (n = 7)||ARQ (n = 5) or ARR (n = 2)||−/−/−/−/−/−||−/−/−/−/−/−||−/−/−/−/−/−|
n = number of animals tested. Samples were tested in duplicate in separate assays *AFRQ/AFRQ substrate where F represents amino acid at position 141. The AFRQ/AFRQ genotype is more commonly associated with atypical scrapie . ND = not done. +/− symbols show the amplification outcome for each animal.
Thorne et al.
Thorne et al. BMC Veterinary Research 2012 8:223 doi:10.1186/1746-6148-8-223